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爱丁堡大学\University of Edinburgh医学类论文指导:Cyst Pills preparation

论文价格: 免费 时间:2013-10-13 23:39:38 来源:www.ukassignment.org 作者:留学作业网
Ovarian cyst is a lump appear on the ovaries containing liquid fraction. Ovarian tissue atypia large , prone to various cysts, and varied in nature , there are benign , malignant , physiologic , pathologic . First of all to confirm the diagnosis, the treatment to be effective . After diagnosis , indications for surgery Western preferred surgical treatment , such as cysts smaller cysts usually grow until after surgery . No cure in Western medicine can cure , waiting for surgery this time , you can use TCM Treating Endometriosis methods such as treatment with Western medicine , the clinical effect is good , can be eliminated, reduced or controlled ovarian cysts ovarian cysts grow and eventually avoid painful surgery patients [ 1 ] . Hospital 's pharmaceutical cyst Pills is a pill with reducing swelling , Blood and Water of the effect, for the treatment of women with ovarian cysts, clinically significant effects were observed .
卵巢肺脓肿是指卵巢上涌现的肿块含有液性全体。卵巢机构异形性大,简单发作各族肺脓肿,且本质各别,有良性、恶性,有生感性、病感性。率先要明白确诊,能力无效医治。诊断后,有手术指征者中医首运动员术医治,如肺脓肿较小,一般会待到肺脓肿长成后再行手术。

A preparation process
1.1 prescription form
Qumai 450 g, Guizhi 90 g, Poria 150 g, moutan 90 g, seaweed 150 g, Mustard Seed 90 g, pangolin ( system ) 90 g, Tri 100 g, Siphonostegia 150 g, Astragalus 150 g, Atractylodes ( fried ) 90 g, Millettla 150 g, red peony root 90 g, diffusa 180 g, Curcuma 90 g.
1 制备工艺
1.1 便条构成
瞿麦450 g、桂枝90 g、茯苓150 g、国花皮90 g、海藻150 g、白芥子90 g、鲮鲤(制)90 g、三棱100 g 、刘寄奴150 g、黄芪150 g、白术(炒)90 g、鸡血藤150 g、赤芍90 g 、五步蛇舌草180 g、莪术90 g。

1.2 Method
More than 15 kinds , including Mustard Seed , Poria, Moutan , seaweed, pangolin ( system ) , Curcuma , TPG and Atractylodes ( fried ) 9 herbs crushed into fine powder , sifted , and mix. The remaining Qumai , Gui , Siphonostegia , Astragalus, Millettia, and diffusa six herbs boiling water 2 times 2 h, filtered, and the combined filtrate was concentrated to a relative density of 1.35 to 1.40 ( 50 ℃) Qing cream. Take clear cream added to the above powder , mix , machine-made pills, drying, ie .

2 Quality Control

2.1 Characters
This product is dark brown pill , spicy , bitter.

2.2 Identification

2.2.1 to take the goods, set under the microscope : irregular branched clumps colorless , water chloral hydrate liquid melt ; mycelium colorless , diameter 4 ~ 6 μm. Calcium oxalate crystals present in the colorless parenchyma cells , sometimes arranged in several rows . Bordered pits catheter colorless or orange , bordered pits arranged closely . Calcium oxalate crystal small , long 10 ~ 32 μm, irregularly clustered in the parenchyma cells , stone cells yellow. Fiber bundles surrounding cells containing calcium oxalate crystal formation crystal fibers.

2.2.2 take this product 6 g, small study, n-butanol 100 ml, ultrasonic treatment 1 h, filtered and the filtrate was washed with 1 % sodium hydroxide solution 3 times 35 ml, discard the lye , following with n-butanol saturated with water until neutral , discard the liquid water , n-butanol solution evaporated on a water bath , dissolve the residue in 1 ml of methanol , as the test solution . Another Astragaloside reference substance, add methanol produced per 1 ml contains 1 mg of solution as the reference solution. Thin layer chromatography ( Chinese Pharmacopoeia 2005 edition an Appendix VI B) test, to learn the test solution 10 μl, reference solution 2 μl, respectively, points on the same silica gel G plate with chloroform - ethyl acetate - methanol - water (10:20:11:5) 10 ℃ placed below the lower solution as the agent , started out , dried, sprayed with 10% sulfuric acid in ethanol , heated at 105 ℃ for about 5 min. Test products for chromatography, chromatography with reference substance corresponding position was the same tan colored spots ; UV light (365 nm) , under review was the same orange and yellow fluorescent spots [ 2 ] .

2.3 Inspection
Should be consistent with the pills under the relevant provisions of the ( Chinese Pharmacopoeia 2005 edition an appendix IA).

Three clinical observation

3.1 Case Selection
All patients from the hospital outpatients, was diagnosed as ovarian cysts, ovarian cysts and 2.0 cm ≤ diameter <8.0 cm [3] ( hospital ultrasound examination report data ) , a total of 220 cases , aged 25 to 55 years old.

3.2 Treatment
After examination diagnosed ovarian cysts meet the above conditions , giving cyst Pills 6 g / times , 1 d 3 times a day, orally. 1 month to 1 course of treatment.

3.3 Clinical Observation
Clinical observation of all single- blinded , controlled efficacy before and after treatment , with no control group [ 4 ] , taking a full course of treatment to make a second ultrasound review, the treatment results were compared.

3.4 Clinical Standards
① cure: after medication , the symptoms disappear , ultrasonography cysts disappear. ② improved: After medication , the symptoms disappeared, ultrasonography cyst reduced by half compared with the first visit . ③ invalid: medication , the symptoms did not change, no change in cyst size ultrasonography .

3.5 Treatment Results
After taking a course of treatment , 85 cases were cured , improved in 125 cases , ineffective in 10 cases , the cure rate was 38.64% , total effective rate was 95.45% . After taking two courses , 135 cases were cured , improved in 78 cases , 7 cases , the cure rate was 61.36% , total effective rate was 96.82% . Looking at the results from the treatment , cysts Pills for treatment of ovarian cysts results are satisfactory, but taking two courses of medication a cure rate significantly higher than the course of treatment, the total effective rate was no significant difference.

4 Discussion
The party started to develop , in order to direct water pan pill, but prescription medicine Qumai , Gui , Siphonostegia , Astragalus, Millettia, diffusa containing fibrous ingredients such as too much light and crushed leavening , viscosity difference , the direct effect of poor pill , so the preparation process for the pill to improve the above herbal extracts , concentrated into a clear paste , then mixed with other drugs , pill made ​​good effect .

Quality control, using microscopic identification and TLC identification, can effectively control the quality of preparation , quality control standards meet Shandong Province Food and Drug Administration requirements.

Gynecological ovarian cysts , under the Chinese "Zhengjia " category, with its multi- righteousness weak , blood disorders , specific cause to qi stagnation , blood stasis , phlegm most common, as impassioned internal injuries , liver qi stagnation, poor blood, or menstruation , postpartum , the frail , the evils invasion , or bleeding lag , or spleen wet stagnation, phlegm gather together , qi stagnation , blood stasis , phlegm mutual knot together in the cell , forming Zhengjia , disease Jia de facto , the evil was even worse righteousness callus , and therefore the disease until late and often jumbled actual situation , the formation of chronic illness.

Hospital 's pharmaceutical cyst Pills to Qumai RRI mainly with Curcuma , Siphonostegia , red peony, tree peony bark , pangolin ( system ) , Millettla , blood circulation, relieves congestion , Gui also Yang relieves congestion , seaweed, Mustard Seed Xiaotansanjie , diffusa detoxification Sanjie , Astragalus , Atractylodes ( fried ) Qi righting , various drugs , played a total of blood and Water , Xiaotansanjie , righting effect , coincide with the pathogenesis of this disease , it used to be received good effect. The formulations are easy to take , low cost, almost no recurrence after healing , reaching seeking this treatment , the therapeutic effect of treating the symptoms , clinically achieved good results.
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